Schizophrenia Relapse Reduction Program

As part of our dedication to providing you leading insights in schizophrenia, Otsuka Pharmaceutical Development & Commercialization, Inc. is pleased to offer the Frameworks in Health and Quality: Schizophrenia Relapse Reduction Program.

Schizophrenia is a chronic, relapsing, and disabling disorder characterized by symptoms such as hallucinations and delusions, disorganized thinking, affective flattening, apathy, and social withdrawal. Schizophrenia is characterized by recurrent episodes of relapse of psychotic symptoms. The risk of relapse is great, with the 1-year rate as high as 50 percent and the 5-year rate as high as 80 percent. Prevention of relapse is one crucial goal of long-term therapy in schizophrenia.

This program is a set of unbranded resources for healthcare stakeholders—payers, providers, patients, and caregivers. The program aims to support emerging clinical market dynamics and opportunities as they relate to schizophrenia relapse reduction.

Program objectives:

  • Assist and complement relapse reduction efforts
  • Enhance communication among all stakeholders
  • Provide stakeholders with relapse educational materials for patients and caregivers
  • Emphasize patient wellness and adherence to treatment plans
  • Promote other important relapse reduction topics such as medication reconciliation, transitions of care, and quality measures

This disease management program supports payers, providers, patients, and caregivers.


Program introductory materials and key issues for payers including HEDIS® quality improvement guidance resources and disease management program components.

Click here to view these resources.

Healthcare Providers

Program introductory materials and education and awareness resources for providers, community mental health centers, case managers, hospital treatment teams, social workers, and other patient advocates; including relapse and disease management, treatment adherence, and medication reconciliation resources

Click here to view these resources.

Patients* and Caregivers

Healthcare professionals may choose to share program materials with patients and their caregivers. Program materials include schizophrenia and relapse education and awareness resources that include tools for relapse action planning, treatment adherence, and hospitalization resources. All patient and caregiver resources are also available in Spanish.

Click here to view these resources.

Relapse Reduction and Schizophrenia

Because relapse in schizophrenia is associated with a heavy financial and human burden, its reduction has become an important goal. Implementation of disease management strategies may help improve care coordination, relapse reduction, and clinical outcomes for patients with schizophrenia.

*Frameworks resources use patient and consumer interchangeably.

Frameworks resources are intended for educational purposes only and are intended for healthcare professionals and/or payer representatives who may choose to share some of these resources with patients or their caregivers. Healthcare professionals should use independent medical judgment when considering Frameworks educational resources. Patients and caregivers should discuss Frameworks materials with a healthcare professional. They are not intended as, nor are they a replacement for, medical advice and treatment from a healthcare professional. Frameworks resources are not intended as reimbursement or legal advice. Users should seek independent, qualified professional advice to ensure their organization is in compliance with the complex legal and regulatory requirements governing healthcare services, and that treatment decisions are made consistent with the applicable standards of care. Frameworks is sponsored by Otsuka Pharmaceutical Development & Commercialization, Inc.